CAS: 2222067-12-9

Pro-GA is a γ-glutamyl cyclotransferase (GGCT) inhibitor with cell permeability, acting as a diester prodrug with anticancer properties. GGCT is a key enzyme in glutathione metabolism and is involved in the ferroptosis pathway. Pro-GA exhibits an IC50 value of 57 μM against the bladder cancer cell line T24, making it useful for cancer research.