CAS 22255-10-3: α-Amyrin palmitate

alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats.

α-Amyrin palmitate is a bioactive compound, which is a natural triterpenoid ester of α-amyrin. This compound is commonly derived from plant sources, particularly those found in various resinous plants and tree barks. α-Amyrin is often extracted and subsequently esterified to form the palmitate derivative, enhancing its stability and bioavailability. The mode of action of α-Amyrin palmitate primarily involves modulation of inflammatory pathways. It is known to inhibit the production of pro-inflammatory mediators, such as prostaglandins and cytokines, by downregulating key enzymes like cyclooxygenase (COX) and 5-lipoxygenase (5-LOX). This mechanism contributes to its significant anti-inflammatory and analgesic effects, making it a promising agent in the development of anti-inflammatory therapies. In terms of applications, α-Amyrin palmitate is extensively studied for its potential therapeutic benefits in the treatment of various inflammatory conditions, including arthritis and dermatitis. Its integration into pharmaceutical formulations and topical applications has been of particular interest to researchers aiming to harness its therapeutic potential. Further exploration into its pharmacokinetics and optimization for clinical use continues to be an area of active scientific investigation.