CAS: 2226534-49-0

Y06137

Y06137, selective BET inhibitor, Kd 81 nM for BRD4(1), researched for castration-resistant prostate cancer treatment.

5-[1-(Cyclohexylmethyl)-6-[(3S)-3-methylmorpholin-4-yl]benzimidazol-2-yl]-3-methyl-1,2-benzoxazole is a ligand that specifically binds to the dopamine D2 receptor. It is also an activator of this receptor. This compound has been used as a research tool in cell biology and ion channels studies. The binding of 5-[1-(Cyclohexylmethyl)-6-[(3S)-3-methylmorpholin-4-yl]benzimidazol-2-yl]-3-methyl-1,2-benzoxazole to the D2 receptor leads to activation of G protein signaling pathways and inhibition of adenylyl cyclase activity. 5-[1-(Cyclohexylmethyl)-6-[(3S)-3-methylmorpholin-4-yl]benzim