CAS 223769-64-0: Benzenecarboximidamide,4-[2-[4-(aminoiminomethyl)phenyl]ethenyl]-3-hydroxy-,dimethanesulfonate (salt)

Hydroxystilbamidine bis(methanesulfonate) is a drug used to treat amoebiasis. It is an amebicidal agent that inhibits the growth of the parasite by acting on the kinetoplast, which is a structure in the cytoplasm of an amoeba. Hydroxystilbamidine bis(methanesulfonate) also prevents the synthesis of DNA in tissue culture cells and has been shown to inhibit toll-like receptor activity in human leukocytes. This drug can be used as a fluorescent probe for DNA and RNA, and has been shown to bind to hydroxyl groups in tissues. It also has a disulfide bond that can be activated with reducing agents such as sodium borohydride or dithiothreitol. Hydroxystilbamidine bis(methanesulfonate) binds to proteins and is readily soluble in water, making it suitable for use in

Hydroxystilbamidine bis(methanesulfonate) is a dye capable of binding to both DNA and RNA. It also is a potent inhibitor of cellular ribonucleases.