![rel-[4-Amino-2-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamino]-5-thiazolyl](2-nitrophenyl)methanone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F350511-rel-4-amino-2-1r-2r-4s-bicyclo-2-2-1-hept-2-ylamino-5-thiazolyl-2-nitrophenyl-methanone.webp&w=3840&q=75)
CAS 2237942-08-2: rel-[4-Amino-2-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamino]-5-thiazolyl](2-nitrophenyl)methanone
Formula:C17H18N4O3S
InChI:InChI=1/C17H18N4O3S/c18-16-15(14(22)11-3-1-2-4-13(11)21(23)24)25-17(20-16)19-12-8-9-5-6-10(12)7-9/h1-4,9-10,12H,5-8,18H2,(H,19,20)/t9-,10+,12+/s2
InChI key:InChIKey=JRNXAQINDCOHGS-QJUVKGSQNA-N
SMILES:N([C@@H]1[C@@]2(C[C@](C1)(CC2)[H])[H])C=3SC(C(=O)C4=C(N(=O)=O)C=CC=C4)=C(N)N3
Synonyms:- MC 180295
- (rel)-MC 180295
- Methanone, [4-amino-2-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamino]-5-thiazolyl](2-nitrophenyl)-, rel-
- rel-[4-Amino-2-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamino]-5-thiazolyl](2-nitrophenyl)methanone
Sort by
Found 4 products.
MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg56.00€5mg131.00€10mg187.00€25mg319.00€50mg449.00€100mg638.00€200mg842.00€1mL*10mM (DMSO)143.00€MC180295
CAS:MC180295 is a bromodomain inhibitor that binds to the CDK4/6-associated bromodomain and inhibits its activity. MC180295 has synergistic effects with venetoclax, which is an inhibitor of Bcl-2. This drug has been shown to be effective against cancer cells in vitro and in vivo, and also sensitizes cancer cells to other drugs. MC180295 is a molecule that suppresses the expression of suppressor genes. It has been shown to be effective at doses of 10 μM or higher in both cell culture and experimental animals.Formula:C17H18N4O3SPurity:Min. 95%Molecular weight:358.41 g/mol
