CAS 225101-69-9: L-Alanine-2,3,3,3-d4,N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (9CI)

Applications N-Fmoc-L-alanine-d4 is the isotope labelled analog of N-Fmoc-L-alanine (F619945); the Fmoc-protected form of L-Alanine (A481500). L-Alanine is used to make in-vivo measurement of glucose and alanine metabolism in studies of patients with diabetes. L-Alanine is a non-essential amino acid for human development and is one of the 20 amino acids encoded by the genetic code. References Bier, D.M. et al.: Diabetes, 26, 1005 (1977); Capaldo, B. et al.: J. Clin. Endocrinol. Metab., 71, 1220 (1990); Giacca, A. et al.: Diabetes, 47, 1763 (1998)

Please enquire for more information about Fmoc-[D4]Ala-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fmoc-(D₄)-Ala-OH was used by Bowman and Zaia in the SPPS of peptide tags for the stable isotopic labeling of carbohydrates which allowed their mass spectroscopic quantification. For ²H-NMR-studies on the influence of Pro on the folding of WALP transmembrane peptides, Koeppe’s group incorporated pairs of deuterated alanines by introducing Fmoc-(D₄)-Ala-OH (60-100%) at selected sequence positions.