CAS 226700-81-8: Fosamprenavir calcium
Formula:C25H36N3O9PS·Ca
InChI:InChI=1S/C25H36N3O9PS.Ca/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21;/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32);/t21-,23-,24+;/m0./s1
InChI key:InChIKey=XOGQXKBFJZURRD-HQROKSDRSA-N
SMILES:[C@H]([C@H](CC1=CC=CC=C1)NC(O[C@H]2CCOC2)=O)(CN(S(=O)(=O)C3=CC=C(N)C=C3)CC(C)C)OP(=O)(O)O.[Ca]
Synonyms:- Calcium [(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonatooxy-butan-2-yl]carbamate
- Carbamic acid, [(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, C-[(3S)-tetrahydro-3-furanyl] ester, calcium salt (1:1)
- Fosamprenavir calcium salt
- Gw 433908G
- Lexiva
- Telzir
- calcium (2R,3S)-1-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-4-phenyl-3-({[(3S)-tetrahydrofuran-3-yloxy]carbonyl}amino)butan-2-yl phosphate
- carbamic acid, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-, (3S)-tetrahydro-3-furanyl ester, calcium salt (1:1)
- Fosamprenavir calcium
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Found 8 products.
Fosamprenavir calcium salt
CAS:Fosamprenavir calcium salt is a prodrug of the antiviral drug amprenavir that is converted to amprenavir in human serum. It is used in combination with other drugs for the treatment of HIV infection. Fosamprenavir calcium salt has a high degree of cytotoxicity, which may be due to its ability to inhibit activation of toll-like receptor 4 and its downstream signaling pathways. In addition, fosamprenavir calcium salt has been shown to inhibit benzalkonium chloride-induced neutrophil chemotaxis, suggesting that it may have anti-inflammatory effects. Fosamprenavir calcium salt also binds to pharmacological agents such as cyclosporine, erythromycin, and indinavir sulfate through competitive inhibition. This binding prevents the formation of an active complex with the enzyme UGT1A4 that is required for glucuronidation and excretion from the body.Formula:C25H34CaN3O9PSPurity:Min. 95%Molecular weight:623.67 g/molFosamprenavir calcium
CAS:Formula:C25H34CaN3O9PSPurity:98%Color and Shape:SolidMolecular weight:623.6689Fosamprenavir Calcium
CAS:Formula:C25H34N3O9PS·CaColor and Shape:White To Off-White SolidMolecular weight:583.59 40.08Fosamprenavir Calcium Salt
CAS:Controlled ProductApplications HIV protease inhibitor; water soluble prodrug of amprenavir. References Falcoz, C., et al.: J. Clin. Pharmacol., 42, 887 92002), Chapman, T.M., et al.: Drugs, 64, 2101 (2004)Formula:C25H34N3O9PS·CaColor and Shape:White To Off-WhiteMolecular weight:623.67Fosamprenavir Calcium
CAS:Sulfonamides used as drugsFormula:C25H34CaN3O9PSColor and Shape:White Off-White PowderMolecular weight:623.13793Fosamprenavir-d4 Calcium Salt
CAS:Controlled ProductApplications HIV protease inhibitor; water soluble prodrug of amprenavir. References Falcoz, C., et al.: J. Clin. Pharmacol., 42, 887 92002), Chapman, T.M., et al.: Drugs, 64, 2101 (2004)Formula:C25H30D4CaN3O9PSColor and Shape:NeatMolecular weight:627.69Fosamprenavir Calcium Salt
CAS:Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility.Formula:C25H34CaN3O9PSPurity:99.59%Color and Shape:White Microcrystalline NeedlesMolecular weight:623.67
