CAS: 226711-23-5

Bakkenolide Db is a sesquiterpene lactone, which is a type of natural product derived from certain plant species. It is primarily sourced from plants in the Asteraceae family, such as Petasites japonicus and other closely related species. The mode of action of Bakkenolide Db involves the inhibition of the NF-κB signaling pathway, which plays a crucial role in regulating immune response and inflammation. This compound has been the subject of scientific research due to its notable anti-inflammatory and potential anticancer properties. Inhibition of the NF-κB pathway by Bakkenolide Db can lead to reduced expression of pro-inflammatory cytokines and other molecules involved in chronic inflammation. Additionally, its ability to modulate cellular proliferation and apoptosis makes it a candidate for cancer research, as it could potentially inhibit tumor growth. While research is ongoing to fully understand and validate its therapeutic potential, Bakkenolide Db represents a promising molecule for the development of new treatments targeting inflammatory diseases and cancer, leveraging its unique biochemical interactions.