CAS: 229499-08-5

Applications A potentially related compound in cephalosporin antibacterial compounds. An isomer of Cefuroxime (C248050). References Chavette, R., et al.: J. Med. Chem., 9, 741 (1966), Miyouchi, M., et al.: J. Chem. Pharm. Bull., 38, 1906 (1990), Sugioka, T., et al.: Chem. Pharm. Bull., 38, 1998 (1990),

Δ2-Cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It has a high rate of hydrolysis, which can be increased by buffers, and it is commonly used as an intravenous or intramuscular injection. Δ2-Cefuroxime has two isomeric forms: the cis-isomer and trans-isomer. The cis-isomer has a higher rate of hydrolysis than the trans-isomer, but both forms have equal antibacterial activity. In addition, Δ2-cefuroxime can be converted into erythromycin.