CAS: 2299226-01-8

CBP/p300-IN-3 (P300/CBP-IN-3) is an inhibitor of p300/CBP histone acetyltransferase.

Cbp/P300-in-3 is a small molecule inhibitor, which is synthesized in vitro. It functions by selectively inhibiting the CBP/p300 family of histone acetyltransferases (HATs), essential regulatory proteins involved in chromatin remodeling and transcriptional activation. The inhibitor binds to the active site of these enzymes, hindering their activity, thereby disrupting the acetylation of histones and other substrates. CBP/p300 plays a critical role in various cellular processes, including gene expression regulation, cell cycle progression, differentiation, and development. Thus, Cbp/P300-in-3 is extensively used in research focused on understanding epigenetic regulation and the role of acetylation in various biological contexts. It is particularly valuable in studies investigating cancer pathogenesis, as dysregulation of CBP/p300 is implicated in tumorigenesis. Researchers also employ Cbp/P300-in-3 in exploring therapeutic strategies aimed at modulating epigenetic marks for disease intervention. This inhibitor thus serves as a powerful tool for dissecting the complex signaling pathways governing cell fate and function.

CBP/p300-IN-3