CAS: 2300178-66-7

Pomalidomid-C6-PEG3-butyl-N3 is a click chemistry reagent featuring an azide group and serves as a crosslinker-E3 ligase ligand conjugate.

Pomalidomid-C6-PEG3-butyl-N3 is a compound that consists of pomalidomide linked to a PEG (polyethylene glycol) linker. The PEG linker, also known as pegylation, is a process in which a PEG molecule is attached to another molecule to enhance its properties. In this case, the amido PEG linker connects pomalidomide with the N3 PEG, which contains an azide group. This heterobifunctional PEG product has been developed to improve the pharmacokinetic and pharmacodynamic properties of pomalidomide. Pomalidomide is an immunomodulatory drug that has shown promising results in the treatment of certain types of cancer and autoimmune diseases. By pegylating pomalidomide, it is expected to have increased solubility, stability, and bioavailability. The N3 PEG moiety in Pomalidomid-C6-PEG3-butyl