2-Methyloxazole is a heterocyclic organic compound characterized by a five-membered ring containing both nitrogen and oxygen atoms. It features a methyl group attached to the second carbon of the oxazole ring, which contributes to its unique chemical properties. This compound is typically colorless to pale yellow and may have a distinct odor. 2-Methyloxazole is known for its role in various chemical reactions and can serve as a building block in the synthesis of pharmaceuticals and agrochemicals. It exhibits moderate polarity due to the presence of the nitrogen and oxygen atoms, influencing its solubility in polar solvents. Additionally, 2-methyloxazole can participate in electrophilic aromatic substitution reactions and may act as a ligand in coordination chemistry. Its derivatives are of interest in medicinal chemistry due to potential biological activities, including antimicrobial and antifungal properties. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled.

Oxazole, 2-methyl-

2-Methyloxazole is a chiral amide that inhibits mitochondrial fatty acid synthesis by binding to the enzyme enoyl-CoA hydratase. It also has inhibitory activity against other enzymes in the mitochondrial pathway, such as dihydroceramide desaturase and dihydrolipoamide dehydrogenase. 2-Methyloxazole has been shown to be an effective treatment for cancer and metabolic disorders, such as insulin resistance and nonalcoholic fatty liver disease. This drug may also be useful in treating chronic pain and neuropathic pain associated with cancer. 2-Methyloxazole is a precursor of phorboxazole, which is being studied as a possible treatment for the pandemic H1N1 influenza virus (Covid-19).

CAS 23012-10-4: Oxazole, 2-methyl-

2-Methyloxazole

Ref: 3D-FM144300

2-Methyloxazole

Ref: 10-F239810

OXAZOLE, 2-METHYL-

Ref: IN-DA002LV1