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CAS 23109-05-9: α-Amanitin

Formula:C39H54N10O14S
InChI:InChI=1/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16?,17?,19?,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1
Synonyms:
  • alpha-Amanitin
  • Brn 1071138
  • Cyclic(L-asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl), cyclic (4-8)-sulfide, (R)-S-oxide
  • Hsdb 3458
  • alpha-Amanitine
  • alpha-Amatoxin
  • 9,18-(Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8,9)(1,5,8,11,14)thiatetraazacyclooctadecino(18,17-b)indole, cyclic peptide deriv.
  • 2-[29-(Butan-2-Yl)-21-(3,4-Dihydroxybutan-2-Yl)-2,14-Dihydroxy-11-Oxido-5,8,20,23,24,27,30,33-Octaoxo-1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23A-Octadecahydro-9,18-(Epiminoethanoiminoethanoiminoethanoiminomethano)Pyrrolo[1',2':8,9][1,5,8,11,14]Thiatetraazacyclooctadecino[18,17-B]Indol-6-Yl]Acetamide
  • 2-[(2R,6S,9R,11R,18S,21S,23aS,29S)-29-[(2S)-butan-2-yl]-21-[(2R,3R)-3,4-dihydroxybutan-2-yl]-2,14-dihydroxy-11-oxido-5,8,20,23,24,27,30,33-octaoxo-1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-9,18-(epiminoethanoiminoethanoiminoethanoiminomethano)pyrrolo[1',2':8,9][1,5,8,11,14]thiatetraazacyclooctadecino[18,17-b]indol-6-yl]acetamide
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Found 4 products.
  • α-Amanitin, from Amanita Phalloides
    Apollo Scientific
    + Info

    α-Amanitin, from Amanita Phalloides

    CAS:
    α-Amanitin, from Amanita Phalloides
    Formula:C39H54N10O14S
    Purity:93.6% (310nm) (Typical Value in Batch COA)
    Color and Shape:Powder
    Molecular weight:918.97g/mol

    Ref: 54-BIA8415

    1mg
    314.00€
    5mg
    1,295.00€
  • α-Amanitin
    Targetmol
    + Info

    α-Amanitin

    CAS:
    alpha-Amanitin is the principal toxin of poisonous mushrooms, exerting its toxic function by inhibiting RNA-polymerase II.
    Formula:C39H54N10O14S
    Purity:≥90%
    Color and Shape:Solid
    Molecular weight:918.97

    Ref: TM-T13540

    100µg
    To inquire
    500µg
    To inquire
  • α-Amanitine
    Glentham
    + Info

    α-Amanitine

    CAS:
    Formula:C39H54N10O14S
    Purity:(UV) ≥ 97.0%
    Color and Shape:White to off-white solid
    Molecular weight:918.97

    Ref: 7W-GE9202

    ne
    To inquire
  • α-Amanitin
    Biosynth
    + Info

    α-Amanitin

    CAS:
    a-Amanitin is a cyclic peptide that is found in mushrooms of the genus "Amanita", which can cause toxic effects if eaten. It has been shown to inhibit the growth of cancer cells by inhibiting mitochondrial membrane potential and reducing dna synthesis, as well as by triggering apoptosis. The structural analysis of a-amanitin has shown that it binds to surface glycoproteins on myeloma cells and triggers the activation of toll-like receptors (TLRs), which initiate an immune response against myeloma cells. This cyclic peptide also has been shown to reduce hepatic steatosis in mice by affecting mitochondrial membrane potential and inducing metabolic changes. Indocyanine green, a fluorescent dye, has been shown to prevent α-amanitin toxicity in mice (Wang et al, 2023), and could be a possible antidote to poisoning by Amanita, such as death cap mushroom Amanita phalloides, which is the cause of over 90% of fatal mushroom poisoning.
    Formula:C39H54N10O14S
    Purity:Min. 95 Area-%
    Color and Shape:White Powder
    Molecular weight:918.97 g/mol

    Ref: 3D-FA57619

    1mg
    610.00€
    5mg
    1,498.00€
    10mg
    2,653.00€
    25mg
    6,439.00€
    50mg
    9,644.00€