CAS: 23593-71-7

Impurity Clotrimazole EP Impurity B Applications para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents. References Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004);

Clotrimatrozole imp B ep is a peptide that is used as a research tool for the study of ion channels and protein interactions. It has been shown to function as an inhibitor of potassium ion channels, which are important in the regulation of nerve and muscle function. Clotrimatrozole imp B ep binds to the extracellular receptor-binding domain (ECD) of its target protein, thereby inhibiting its interaction with ligands or other proteins. Clotrimatrozole imp B ep also inhibits protein interactions with membrane-bound receptors, such as G-protein coupled receptors (GPCRs). This inhibition can be blocked by adding an antibody that binds to the ECD domain.