1H-Indole, 4,7-dimethoxy- is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. The presence of two methoxy groups (-OCH3) at the 4 and 7 positions of the indole ring significantly influences its chemical properties and reactivity. This compound is typically a white to off-white solid and is soluble in organic solvents such as ethanol and dichloromethane, but may have limited solubility in water. It exhibits interesting biological activities, making it of interest in medicinal chemistry and pharmacology. The methoxy substituents can enhance the compound's lipophilicity and may affect its interaction with biological targets. Additionally, 1H-Indole, 4,7-dimethoxy- can undergo various chemical reactions, including electrophilic substitutions and oxidation, which are common for indole derivatives. Its unique structure and properties make it a valuable compound for research in various fields, including organic synthesis and drug development.

1H-Indole, 4,7-dimethoxy-

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4,7-Dimethoxy-1H-indole

4,7-Dimethoxyindole is a synthetic indole alkaloid that has been found to be active against Leishmania and Toxoplasma. It is also an atypical drug with regiospecificity for the parasite thp-1 cells. 4,7-Dimethoxyindole was first synthesized in 1990 as a potential antipsychotic drug. The compound is not cytotoxic to human cells and has been shown to have anti-inflammatory effects. It binds to the parasite fatty acid synthase, inhibiting the production of long chain fatty acids. This leads to decreased virulence and reduced infectivity of the parasite.

CAS 23876-39-3: 1H-Indole, 4,7-dimethoxy-

4,7-Dimethoxy-1H-indole

Ref: 10-F633731

4,7-Dimethoxy-1H-indole

Ref: 54-OR322581

4,7-Dimethoxyindole

Ref: 3D-FD00952

1H-Indole, 4,7-dimethoxy-

Ref: IN-DA00I4M7