CAS 23978-09-8: 2,2,2-Cryptand

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Cryptating agent 222

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Cryptating agent 222 reduces distannene & creates ligands with metal ions using a potassium mirror.

Applications 2,2,2-Crypt is used in the synthesis of hybrid metal-organic salts. It is also an impurity in the preparation of Fludeoxyglucose (D232570), a D-Glucose (G595000) derivative used in the synthesis of sugar nucleotides and oligosaccharides. References Marti-R. et al.: New. J. Chem., 38, 1385 (2014);

Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (HODHB) is a hexacyclic trisodium salt of a diaza-polycyclic aromatic hydrocarbon that has been used as an imaging agent for cancer tissues. The HODHB ion is formed in the presence of sodium salts and hydrogen fluoride and reacts with nitrogen atoms to form amyloid protein complexes. These complexes are then detected using diagnostic techniques such as preparative high performance liquid chromatography or titration calorimetry. Thermodynamic data was obtained by studying the reaction solution and reaction mechanism. Pharmacokinetic properties were investigated by measuring the stability of complexes in the blood stream over time.

4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane