CAS 2401-21-0: 1,2-Dichloro-3-iodobenzene

Iodobenzene is a chemical compound that is composed of two benzene rings joined by a single bond. Iodobenzene isomers are also called iodosobenzenes and they contain one or more chlorine atoms. Iodobenzene has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Iodobenzene inhibits the enzyme phospholipase A2, which is involved in the production of prostaglandins. Iodobenzene binds to enzymes by forming a covalent bond with an electron-rich atom such as oxygen, nitrogen or sulfur in the active site of the enzyme. This type of inhibition is called non-nucleoside inhibition because it does not require an intermediate molecule such as ATP or NADH for binding to the enzyme. Carbonyl groups on iodobenzene molecules form strong bonds with nucleophilic groups on enzymes, leading to enzyme inhibition and

1,2-Dichloro-3-iodobenzene