![3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F179343-3-3-2r-3s-3-hydroxy-2-piperidinyl-2-oxopropyl-4-3h-quinazolinone.webp&w=3840&q=75)
CAS 24159-07-7: 3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone
Formula:C16H19N3O3
InChI:InChI=1S/C16H19N3O3/c20-11(8-14-15(21)6-3-7-17-14)9-19-10-18-13-5-2-1-4-12(13)16(19)22/h1-2,4-5,10,14-15,17,21H,3,6-9H2/t14-,15+/m1/s1
InChI key:InChIKey=FWVHWDSCPKXMDB-CABCVRRESA-N
SMILES:O=C1C=2C(N=CN1CC(C[C@@H]3[C@@H](O)CCCN3)=O)=CC=CC2
Synonyms:- 3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]quinazolin-4(3H)-one
- 3-[3-[(2R,3S)-3-Hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone
- 3-{3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one
- 4(3H)-Quinazolinone, 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-
- Dichroin B
- Febrifugin
- Febrifugine
- NSC 315535
- trans-(+)-Febrifugine
- β-Dichroin
- β-Dichroine
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Febrifugine
CAS:Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .Formula:C16H19N3O3Purity:98.27%Color and Shape:SolidMolecular weight:301.34Febrifugine
CAS:Febrifugine is a coumarin derivative that has been shown to be active against malaria in vitro. It is an experimental model for the study of autoimmune diseases, such as multiple sclerosis. Febrifugine also has antimicrobial activity and can be used to treat infectious diseases. The drug inhibits the synthesis of proteins essential for bacterial growth by inhibiting the chorismate synthetase enzyme, which catalyzes the conversion of chorismate into isopentenyl pyrophosphate (IPP). This blockage leads to a loss of mitochondrial membrane potential and inhibition of protein synthesis. Febrifugine also exhibits pharmacokinetic properties that are similar to other anti-malarial drugs, including chloroquine and quinine.Purity:Min. 95%