![(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F347939-2e-n-5-bromo-2-methoxyphenyl-sulfonyl-3-2-2-naphthalenylmethyl-phenyl-2-propenamide.webp&w=3840&q=75)
CAS 244101-02-8: (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
Formula:C27H22BrNO4S
InChI:InChI=1S/C27H22BrNO4S/c1-33-25-14-13-24(28)18-26(25)34(31,32)29-27(30)15-12-21-7-3-5-9-23(21)17-19-10-11-20-6-2-4-8-22(20)16-19/h2-16,18H,17H2,1H3,(H,29,30)/b15-12+
InChI key:InChIKey=ODTKFNUPVBULRJ-NTCAYCPXSA-N
SMILES:C(C1=CC2=C(C=C1)C=CC=C2)C3=C(/C=C/C(NS(=O)(=O)C4=C(OC)C=CC(Br)=C4)=O)C=CC=C3
Synonyms:- 2-Propenamide, N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-, (2E)-
- CM 9
- L 798106
- GW 671021
- (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide
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Found 5 products.
L-798106
CAS:L-798106 (CM9) is an EP3 receptor antagonist that inhibits EP4, EP1, and EP2 receptors and attenuates PGE2-induced cough.Formula:C27H22BrNO4SPurity:98.97%Color and Shape:SolidMolecular weight:536.44L-798106
CAS:Formula:C27H22BrNO4SPurity:≥ 99.0%Color and Shape:White to off-white solidMolecular weight:536.44L-798106
CAS:L-798106 is a potent and selective h1 receptor antagonist that blocks the action of histamine. It has been shown to inhibit the intracellular calcium concentration, which may be due to its inhibition of myosin phosphatase activity. L-798106 also inhibits cancer cells by interfering with cell growth and preventing the production of cancerous proteins. Interestingly, this drug also has a pressor effect on blood pressure, which may be due to its ability to increase camp levels in the mesenteric artery. L-798106 is an antagonist of epoxyeicosatrienoic acids (EETs) and 2-aminoethoxydiphenyl borate (2-APB). These compounds are potent agonists for the h1 receptor, which causes vasoconstriction and increases in blood pressure. L-798106 has been shown to inhibit protein synthesis at polymerase chain reaction (PCR) levels in prostate cancer cells. This drug also decreasesFormula:C27H22BrNO4SPurity:Min. 95%Molecular weight:536.44 g/mol
