CAS: 245747-71-1

NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).

NFAT Transcription Factor Regulator-1

Nfat transcription factor regulator-1 is a biochemical reagent, which is commonly derived from synthetic or recombinant sources. It functions by modulating the activity of NFAT (nuclear factor of activated T-cells) transcription factors, which are crucial in several cellular processes. Through its regulatory action, it influences NFAT's ability to translocate to the nucleus and bind DNA, effectively controlling the transcription of genes involved in immune responses and other cellular activities. Nfat transcription factor regulator-1 is primarily used in research settings to study pathways related to immune function, inflammation, and cell differentiation. By modulating NFAT activity, scientists can elucidate the mechanisms by which immune cells, such as T-cells, are activated and how they contribute to various physiological and pathological processes. Its application is vital for advancing our understanding of immune system regulation, providing insights that could lead to therapeutic advancements in autoimmune diseases and other conditions involving dysregulated immune responses.