CAS: 247050-21-1

3-(Fluoromethyl)-3,4-Dihydro-1(2H)-Isoquinolinone is a small molecule that has been shown to induce muscle cell apoptosis. 3-(Fluoromethyl)-3,4-Dihydro-1(2H)-Isoquinolinone binds to and inhibits the activity of mir-27a, a microRNA that is involved in regulating muscle development and muscle regeneration. The inhibition of mir-27a leads to the activation of apoptotic pathways. 3-(Fluoromethyl)-3,4-Dihydro-1(2H)-Isoquinolinone also enhances the activity of other molecules that are involved in apoptosis (e.g., caspases). This compound can be used as a therapeutic strategy for the treatment of muscle degeneration caused by disorders such as Duchenne muscular dystrophy or cancer.