CAS 2471-70-7: 6-Methoxy-2-naphthoic acid

Impurity Naproxen USP Related Compound A Applications An impurity of Naproxen (N377525) with bactericidal and fungicidal activity. A metabolite of Nabumetone (N200500). Naproxen USP Related Compound A. References Khorana, M.L. et al.: J. Pharmac. Sci., 56, 993 (1967); Ray, J.E. et al.: J. Chrom. Biomed. Appl., 336, 234 (1984);

6-Methoxy-2-naphthoic acid

6-Methoxy-2-naphthoic acid (MN) is a cavity amide that has been shown to have an inhibitory effect on the growth of cancer cells. MN has been found to be more effective in inhibiting β-amyrin than caffeine, which may be due to its increased lipophilicity. It also has a higher affinity for adriamycin and enhances its anticancer effects. MN has been shown to be beneficial in treating diabetic patients, as it can reduce blood glucose levels by stimulating insulin release. The pharmacokinetic properties of MN are similar to those of other cavity amides, with rapid absorption and distribution throughout the body. This compound is metabolized in the liver by CYP2C8, CYP2C9, CYP3A4 and CYP3A5 enzymes. Molecular docking analysis of MN with β-amyrin showed that there was a strong interaction between them due to their complementary shapes and charge distributions

6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

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Naproxen impurity standard

6-Methoxy-2-naphthoic acid