CAS: 2474876-09-8

GSK046

GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.

GSK046 is a potent inhibitor of kinases that has shown promising results in the treatment of leukemia and other types of cancer. It works by blocking the activity of specific proteins that are involved in cell growth and division, leading to apoptosis (cell death) in cancer cells. GSK046 has been found to be effective against both Chinese hamster ovary cells and human cancer cells. This medicinal compound has been shown to induce cell cycle arrest, preventing the proliferation of cancerous cells. GSK046 is an innovative anticancer agent with the potential to revolutionize cancer treatment.