CAS: 2502156-03-6
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Found 3 products.
(2S,4R)-1-((S)-2-(3-(3-((S)-2-(((7-(8-Chloronaphthalen-1-yl)-4-((S)-3-(cyanomethyl)-4-(2-fluoroacryloyl)piperazin-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)oxy)methyl)pyrrolidin-1-yl)propoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CAS:Formula:C59H71ClFN11O7SPurity:98%Color and Shape:SolidMolecular weight:1132.7809LC-2
CAS:LC-2 is a peptide that inhibits the activation of the protein tyrosine kinase. It is a potent inhibitor of the receptor-tyrosine kinase, KDR. LC-2 blocks activation of KDR by inhibiting binding to its ligand, VEGF. The LC-2 peptide is also an activator for some receptors, including the beta-adrenergic receptor and the angiotensin II type 1 receptor. LC-2 is a high purity synthetic peptide that can be used as a research tool in pharmacology, cell biology, and biochemistry.Formula:C59H71ClFN11O7SPurity:Min. 95%Molecular weight:1,132.8 g/molLC-2
CAS:LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is aFormula:C59H71ClFN11O7SPurity:98%Color and Shape:SolidMolecular weight:1132.78
