CAS 2503-13-1: 4,10,16-trimethyl-6,12,18-tris(1-methylethyl)-3,9,15-tris(1-methylpropyl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

Enniatin A is a cyclic depsipeptide, which is a secondary metabolite produced by certain Fusarium fungi. It functions as an ionophore, facilitating the transport of ions across cellular membranes. This activity stems from its ability to form complexes with metallic cations, disrupting ion gradients and membrane potential. As a result, Enniatin A can affect various cellular processes, including signal transduction and energy metabolism. Enniatin A has garnered interest in the scientific community due to its potential applications in agriculture and medicine. In agriculture, its antifungal and antibacterial properties could be leveraged to develop natural pesticides. In medicine, its cytotoxic activity is being explored for potential anticancer therapies. However, its exact mechanism remains a subject of ongoing research, with studies focusing on its interactions at the molecular level. Enniatin A's bioactivity underlines its significance as a tool for studying ion transport and cellular homeostasis. Continued investigation into this compound could reveal further applications and enhance our understanding of cellular processes affected by ion gradients.

Enniatin A, a Fusarium toxin, blocks rat liver ACAT with 22 μM IC50.

Enniatin A