CAS 2524-49-4: 3-Buten-1-amine

3-Buten-1-amine is an acylation product that is obtained by the reaction of hydrochloric acid with an epoxide and ammonia or an amine. It can also be obtained by the reaction of a β-amino acid and formaldehyde, followed by hydrolysis. 3-Buten-1-amine has been shown to be a nucleophile in asymmetric synthesis reactions and it is used as a chiral auxiliary. This compound can be used to synthesize homoallylamines, metathesis reactions, allyl carbonate, and amides. 3-Buten-1-amine has been shown to react with thionyl chloride to produce oxirane compounds that are used as signal detection agents in chromatography.

3-Buten-1-amine is an aliphatic terminal amine used for organic synthesis and in proteomics research. Its hydrochloride salt is used to improve the detection of neurodegenerative alzheimer’s disease in ELISA titrations by reducing the background due to non-specific associations of molecules and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.