CAS 252917-06-9: GSK 3 inhibitor XVI
Formula:C22H18Cl2N8
InChI:InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
InChI key:InChIKey=AQGNHMOJWBZFQQ-UHFFFAOYSA-N
SMILES:ClC1=C(C=2C(=CN=C(NCCNC3=CC=C(C#N)C=N3)N2)C=4NC(C)=CN4)C=CC(Cl)=C1
Synonyms:- 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-
- 3-Pyridinecarbonitrile, 6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-
- 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
- Chir 911
- Chir 99201
- Chir-99021
- Chir99021
- Cihr 99021
- Ct 99021
- GSK 3 inhibitor XVI
- Gsk 3Ixv
- See more synonyms
Sort by
Found 10 products.
CHIR 99021 Hydrochloride Salt
CAS:Controlled ProductApplications CHIR 99021 Hydrochloride is an inhibitor of glycogen synthase kinase 3, which mimics Wnt signaling in preadipocytes. CHIR 99021 stabilizes free cytosolic β-catenin and inhibits adipogenesis by blocking induction of CCAAT/enhancer-binding protein α and peroxisome proliferator-activated receptor γ. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bennett, C., et al.: J. Bio. Chem., 277, 30998 (2002);Formula:C22H18Cl2N8•xHClColor and Shape:NeatMolecular weight:465.343646CHIR 99021 [Optimized for Cell Culture]
CAS:Formula:C22H18Cl2N8Purity:>97.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:465.34CHIR 99021
CAS:Potent and selective inhibitor of the glycogen synthase kinase GSK-3. Promotes cell renewal in embryonic stem cells by modulating Notch, MAPK and TGF-β signalling pathways, which are involved in pluripotency. It also affects the Wnt/β-catenin pathway and alters expression of genes coding for proteins, epigenetic regulatory elements and non-coding RNAs. The combination of CHIR 99021 and basic fibroblast growth factor (bFGF) allows long-term self-renewal in adult mouse retinal progenitor cells.Formula:C22H18Cl2N8Purity:Min. 95%Color and Shape:PowderMolecular weight:465.34 g/molCHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Formula:C22H18Cl2N8Purity:97.94% - ≥95%Color and Shape:SolidMolecular weight:465.34Ref: TM-T2310
2mg43.00€5mg64.00€10mg96.00€25mg160.00€50mg254.00€100mg404.00€200mg603.00€500mg938.00€1mL*10mM (DMSO)70.00€CHIR99021
CAS:CHIR99021Formula:C22H18Cl2N8Purity:By hplc: >99% (Typical Value in Batch COA)Color and Shape: off-white to beige solidMolecular weight:465.34g/molCHIR-99021-d4
CAS:Controlled ProductFormula:C22D4H14Cl2N8Color and Shape:NeatMolecular weight:469.363[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
CAS:Formula:C22H18Cl2N8Purity:98%Color and Shape:SolidMolecular weight:465.3379CHIR 99021
CAS:Formula:C22H18Cl2N8Purity:>97.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:465.34
![CHIR 99021 [Optimized for Cell Culture]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FC4010.jpg&w=3840&q=75)
![[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyrid…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00385A.jpg&w=3840&q=75)
