CAS 261733-18-0: 4,6-Bis(diphenylphosphino)phenoxazine

4,6-Bis(diphenylphosphino)phenoxazine, min. 98% NIXANTPHOS

The optimal reaction conditions for the cross-coupling of aryl halides with diphosphines are known. The reaction is catalyzed by palladium and is an efficient method for the synthesis of alkenes and alkynes. In this process, a nucleophilic attack on the carbon atom in the phosphine occurs, which generates a reactive intermediate that can undergo hydrogen bonding interactions with the aryl halide. This reaction is also called "Pd-catalyzed cross-coupling." The reaction proceeds through two steps: (1) oxidative carbonylation of the phenoxazine to form an enolate intermediate and (2) reductive elimination of chlorine from the chloroformate. The synergic effect between two molecules is seen when one molecule has a structural property that enhances or diminishes another molecule's properties. For example, if one molecule has a high electron density, then it may be able to stabilize negative charge on another molecule's atoms; if

4,6-Bis(diphenylphosphino)phenoxazine used as an intermediate in the manufacture of pharmaceuticals, agrochemicals, dyestuffs, fine chemicals, medical and material synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

4,6-Bis(diphenylphosphino)-10H-phenoxazine