Ethyl 4-(2-chloroacetamido)benzoate, with the CAS number 26226-72-2, is an organic compound characterized by its ester functional group and an amide substituent. It features a benzoate structure, where the ethyl group is attached to the carboxylate portion, and a 2-chloroacetamido group is substituted at the para position of the aromatic ring. This compound is typically a white to off-white solid, and it is soluble in organic solvents such as ethanol and acetone, but may have limited solubility in water due to its hydrophobic aromatic structure. Ethyl 4-(2-chloroacetamido)benzoate may exhibit biological activity, making it of interest in pharmaceutical research, particularly in the development of new drugs or as an intermediate in organic synthesis. Its reactivity can be attributed to the presence of the chloroacetamido group, which can participate in various chemical reactions, including nucleophilic substitutions. Proper handling and storage are essential, as with many chemical substances, to ensure safety and stability.

ethyl 4-(2-chloroacetamido)benzoate

26226-72-2: Ethyl 4-[(Chloroacetyl)Amino]Benzoate

Ethyl 4-(2-chloroacetylamino)benzoate is a reagent that is used to produce aminosulfonyl chlorides. It can be used as an efficient method for the deacylation of thionylated peptides and proteins. The reaction product, which is a sulfonamide, can be hydrolyzed by acid to give the corresponding carboxylic acid. This reagent also has been shown to inhibit the activity of cytosolic phospholipase A2 in human erythrocytes and has been used as a probe for this enzyme in other systems. The inhibition of this enzyme leads to a decrease in arachidonic acid production, which may have therapeutic potential in diseases such as atherosclerosis.

CAS 26226-72-2: ethyl 4-(2-chloroacetamido)benzoate

Ethyl 4-(2-chloroacetylamino)benzoate

Ref: 3D-FE54252

Ethyl 4-[(chloroacetyl)amino]benzoate

Ref: 10-F365266

Benzoic acid, 4-[(2-chloroacetyl)amino]-, ethyl ester

Ref: IN-DA002SBZ

Ethyl 4-(2-Chloroacetamido)Benzoate

Ref: 54-OR1013192