Z-Gln-OMe, also known as Z-glutamine methyl ester, is a derivative of the amino acid glutamine, where the amino group is protected by a benzyloxycarbonyl (Z) group and the carboxylic acid is esterified with methanol. This compound is characterized by its stability under various conditions, making it useful in peptide synthesis and as a building block in organic chemistry. The Z group provides protection to the amino functionality, allowing for selective reactions without interfering with the amine. Z-Gln-OMe is typically used in the synthesis of peptides and other complex molecules due to its ability to facilitate the formation of peptide bonds while maintaining the integrity of the glutamine side chain. Additionally, the methyl ester can be hydrolyzed to yield the corresponding carboxylic acid, which can be further utilized in various biochemical applications. Overall, Z-Gln-OMe is valued for its versatility in synthetic chemistry and its role in the development of peptide-based therapeutics.

Z-Gln-OMe

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Z-Gln-Ome

L-Glutamine, N2-[(phenylmethoxy)carbonyl]-, methyl ester

Z-L-glutamine methyl ester is a synthetic amino acid that contains the amino acid lysine, which is used in many proteins. It has a nature of an amide and a functional group of an amide. The chemical name for Z-L-glutamine methyl ester is N-[2-(3,5-diiodo-4-hydroxyphenyl)ethyl]-N'-(2-chloroethyl)glycine. This compound has been used as a receptor ligand for the NMDA receptor and ornithine decarboxylase.

Z-L-glutamine methyl ester was identified by mass spectroscopy, proton magnetic resonance (nmr), and infrared spectroscopy. It has been shown to be selective for the NMDA receptor over other receptors including the 5HT1A, α1D adrenergic, muscarinic M1, and σ1 receptors.

CAS 2650-67-1: Z-Gln-OMe

Z-Gln-Ome

Ref: 54-OR1029549

L-Glutamine, N2-[(phenylmethoxy)carbonyl]-, methyl ester

Ref: IN-DA002THZ

Z-L-glutamine methyl ester

Ref: 3D-FG47853

Z-GLN-OME

Ref: 10-F475373