CAS 26819-07-8: N-ethyl-3-methylbenzamide

N-Ethyl-m-toluamide is a chemical enhancer that is used to increase the effectiveness of insecticides and other chemicals. It is used in animal urine samples to test for the presence of drugs, such as amphetamines, cocaine, and cannabinoids. N-Ethyl-m-toluamide is also used in wastewater treatment plants to eliminate bacteria and enhance the removal of organic matter. In addition, it has been shown to be active against human liver cells. The second order rate constant was found to be 6.8 x 10^6 M^(-1) s^(-1) at 25 degrees Celsius. N-Ethyl-m-toluamide can cause skin reactions in people who are exposed to it on a daily basis over an extended period of time. This chemical may also have carcinogenic effects on cells, which may be due to its ability to induce DNA mutations in vitro and promote tumor growth in vivo.

Applications N-Ethyl-m-toluamide is an impurity of DEET (D228500), which is an insect repellent. References Gilbert, I.H., et al.: J. Econ. Entomol., 48, 741 (1955), Ambrose, A.M., et al.: Toxicol. Appl. Pharmacol., 1, 97 (1959), Blomquist, L., Acta Pharmacol. Toxicol., 41, 235 (1977), Yeung, J.M., et al.: Drug Metab. Dispos., 16, 600 (1988),