CAS 268214-51-3: (3R,3aR,5aS,6aR,6bR,9aR,10aS,10bS)-3-[(1R,4E)-1,5-Dimethyl-6-oxo-4-hexen-1-yl]tetradecahydro-3a,10b-dimethyl-7-methylene-8-oxo-6aH-cyclopenta[7,8]cyclopropa[4,4a]naphtho[2,3-b]furan-6a-propanoic acid

Coronalolide is cytotoxic to P-388 cells and anti-HIV; it and its methyl ester are broadly toxic to various human cancer cells.

Coronalolide is a natural compound, which is a secondary metabolite derived from specific plant sources. It is typically extracted from the leaves and stems of certain species found in tropical environments. As a lactone compound, coronalolide exhibits a complex structural framework that allows for various interactions at the molecular level. The mode of action of coronalolide involves its ability to interact with cellular receptors or enzymes, potentially altering biological pathways critical to cellular function. This interaction can be specific, targeting a particular protein or enzyme, making it a candidate for further investigation in the field of medicinal chemistry and pharmacology. Coronalolide is primarily researched for its possible applications in therapeutic settings. The compound is undergoing studies to evaluate its efficacy in modulating pathways relevant to diseases such as inflammation, cancer, and microbial infections. The unique properties of coronalolide make it a subject of interest, promising to contribute to the development of novel pharmaceuticals or as a lead compound in drug discovery. Given its natural origin and potential for modifying biological pathways, coronalolide continues to be a focus of scientific exploration.