L-Thymidine, with the CAS number 26879-47-0, is a nucleoside that plays a crucial role in the synthesis of DNA. It is composed of a thymine base linked to a deoxyribose sugar. This compound is characterized by its ability to participate in the formation of DNA strands, making it essential for cellular replication and repair processes. L-Thymidine is typically a white to off-white crystalline powder that is soluble in water and exhibits a melting point that varies depending on its form. It is often used in molecular biology and biochemistry as a substrate in various enzymatic reactions and as a building block in DNA synthesis. Additionally, L-Thymidine has applications in the pharmaceutical industry, particularly in the development of antiviral and anticancer therapies. Its biological activity is influenced by its structural properties, which allow it to mimic the natural nucleosides found in DNA, thus facilitating its incorporation into nucleic acids during replication.

L-Thymidine

26879-47-0: 1-beta-L-Ribofuranosylthymine, 5-Methyl-1-beta-L-ribofuranosyl-2,4(1H,3H)-pyrimidinedione

Telbivudine Impurity 14

5-Methyl-L-uridine

5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.

L-5-Methyluridine, an L-configuration of 5-Methyluridine, is an endogenous methylated nucleoside present in human fluids.

CAS 26879-47-0: L-Thymidine

Telbivudine Impurity 14

Ref: ST-EA-CP-T232011

5-Methyl-L-uridine

Ref: 7W-GN4369

Telbivudine Impurity 14

Ref: 4Z-T-2515

5-Methyl-L-uridine

Ref: 3D-NM06240

L-5-Methyluridine

Ref: TM-T74653