4-Phenyl-6-(trifluoromethyl)-2-pyrimidinylamine is a chemical compound characterized by its pyrimidine core, which is a six-membered heterocyclic ring containing two nitrogen atoms at positions 2 and 4. The presence of a phenyl group at the 4-position and a trifluoromethyl group at the 6-position contributes to its unique properties. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The trifluoromethyl group enhances its lipophilicity and can influence its biological activity, making it of interest in medicinal chemistry. The amine functional group can participate in hydrogen bonding, which may affect its reactivity and interactions with biological targets. Additionally, the compound may exhibit specific spectral characteristics in techniques such as NMR and IR spectroscopy, allowing for its identification and characterization. Overall, 4-phenyl-6-(trifluoromethyl)-2-pyrimidinylamine is notable for its structural features that may confer unique chemical and biological properties.

4-phenyl-6-(trifluoromethyl)-2-pyrimidinylamine

26974-09-4: 4-Phenyl-6-(Trifluoromethyl)Pyrimidin-2-Amine, 2-Bromo-1,3,4,5,6,7,8-Heptafluoronaphthalene, 2-Amino-4-Phenyl-6-(Trifluoromethyl)Pyrimidine

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.

CAS 26974-09-4: 4-phenyl-6-(trifluoromethyl)-2-pyrimidinylamine

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

Ref: 10-F493999

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

Ref: 3D-NA57415

2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

Ref: 54-PC0914