1H-pyrazolo[3,4-c]pyridine is a heterocyclic organic compound characterized by a fused ring system that includes both pyrazole and pyridine moieties. This compound typically exhibits a planar structure due to the conjugated system of double bonds, which contributes to its stability and potential reactivity. It is often recognized for its role in medicinal chemistry, as derivatives of this compound have been investigated for various biological activities, including anti-inflammatory and anticancer properties. The presence of nitrogen atoms in the ring structure can influence its electronic properties, making it a potential ligand in coordination chemistry. Additionally, 1H-pyrazolo[3,4-c]pyridine is soluble in polar organic solvents, which can facilitate its use in various synthetic applications. Its CAS number, 271-47-6, is a unique identifier that allows for easy reference in chemical databases. Overall, this compound's unique structural features and biological relevance make it a subject of interest in both research and pharmaceutical development.

1H-pyrazolo[3,4-c]pyridine

271-47-6: 1H-Pyrazolo[3,4-c]pyridine, 6-Azaindazole, 1H-Pyrazolo(3,4-c)pyridine, 6-Aza-1H-indazole

1H-Pyrazolo[3,4-c]pyridine

1H-Pyrazolo[3,4-c]pyridine is a potent inhibitor of the ATP binding site in the ATP synthase. It has been shown to inhibit cellular proliferation and induce apoptosis in cancer cells. 1H-Pyrazolo[3,4-c]pyridine binds to and inhibits the activity of Pim-1 kinase. This compound has been shown to be effective against two isoforms of Pim-1 kinase: pim-1A and pim-1B. Substitution of groups on the piperidine ring or at position 3 leads to increased potency against both isoforms, but with different affinities. Evaluation of this compound's effect on tumor growth is ongoing.

CAS 271-47-6: 1H-pyrazolo[3,4-c]pyridine

1H-Pyrazolo[3,4-c]pyridine

Ref: 54-OR30697

1H-Pyrazolo[3,4-c]pyridine

Ref: 10-F079577

1H-Pyrazolo[3,4-c]pyridine

Ref: FT-P12210

1H-Pyrazolo[3,4-c]pyridine

Ref: IN-DA0032RZ

1H-Pyrazolo[3,4-c]pyridine

Ref: 3D-FP51890