CAS 271-73-8: 1H-pyrazolo[3,4-b]pyridine

1H-Pyrazolo[3,4-b]pyridine

1H-pyrazolo[3,4-b]pyridine is a chemical compound that contains a pyrazole ring and a benzene ring. It is an inhibitor of the enzyme acetylcholinesterase and has been shown to be effective for the treatment of diabetic neuropathy. 1H-Pyrazolo[3,4-b]pyridine has also been observed to have anti-inflammatory properties in vitro. The molecule can inhibit the growth of fungi by binding to their cell wall, inhibiting the synthesis of proteins required for fungal cell division. 1H-Pyrazolo[3,4-b]pyridine has been found to bind to both bacterial and human DNA gyrase enzymes, as well as human topoisomerase IV enzymes. This binding blocks their activity and prevents them from maintaining bacterial or human DNA integrity. Hydrochloric acid is used as a catalyst in this reaction. br>br> 1H

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.