CAS 27127-79-3: Thevetin B
Formula:C42H66O18
InChI:InChI=1S/C42H66O18/c1-18-35(60-38-33(50)31(48)29(46)26(59-38)17-55-37-32(49)30(47)28(45)25(15-43)58-37)36(53-4)34(51)39(56-18)57-21-7-10-40(2)20(14-21)5-6-24-23(40)8-11-41(3)22(9-12-42(24,41)52)19-13-27(44)54-16-19/h13,18,20-26,28-39,43,45-52H,5-12,14-17H2,1-4H3/t18-,20+,21-,22+,23-,24+,25+,26+,28+,29+,30-,31-,32+,33+,34-,35-,36-,37+,38-,39-,40-,41+,42-/m0/s1
InChI key:InChIKey=GZVMBXDQUQRICT-RCGIHWJFSA-N
SMILES:O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@@H](O)[C@H](OC)[C@@H](O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O)[C@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C=8COC(=O)C8)[H])[H]
Synonyms:- (3beta,5beta)-3-{[beta-D-glucopyranosyl-(1-> 6)-beta-D-glucopyranosyl-(1-> 4)-(2xi)-6-deoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl]oxy}-14-hydroxycard-20(22)-enolide
- (3β,5β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-<smallcap>L</span>-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
- Thevetin B
- card-20(22)-enolide, 3-[[O-beta-D-glucopyranosyl-(1-> 6)-O-beta-D-glucopyranosyl-(1-> 4)-(2xi)-6-deoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl]oxy]-14-hydroxy-, (3beta,5beta)-
- Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
- (3β,5β)-3-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
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Found 5 products.
Thevetin B
CAS:Thevetin B is a cardiac glycoside, which is a type of organic compound known for its potent effects on the heart. This compound is derived from the seeds of *Thevetia peruviana*, also known as the yellow oleander, a plant native to Central and South America. The primary mode of action of Thevetin B involves inhibition of the Na⁺/K⁺-ATPase pump in cardiac cells. This action results in increased intracellular calcium concentration, leading to enhanced cardiac contractility and a positive inotropic effect. Thevetin B’s ability to modulate cardiac function makes it a subject of research in terms of its potential therapeutic applications for heart conditions, such as heart failure and certain arrhythmias. However, due to its potent activity and narrow therapeutic index, it must be used with caution and precision in clinical settings. Additionally, its toxicological profile necessitates thorough examination and extensive research to fully elucidate safe use parameters. Ongoing studies are investigating its broader pharmacological impacts and potential applications in modern medicine, acknowledging its traditional use in folk remedies while ensuring scientific rigor in evaluation.Formula:C42H66O18Purity:Min. 95%Molecular weight:859.96 g/molThevetin B
CAS:Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.Formula:C42H66O18Purity:98%Color and Shape:SolidMolecular weight:858.96
