2-Amino-N-phenylbenzenesulfonamide, also known as sulfanilamide, is an organic compound characterized by the presence of an amino group and a sulfonamide functional group attached to a phenyl ring. This compound typically appears as a white to off-white crystalline solid and is soluble in water, which is a notable feature of sulfonamides. It exhibits properties such as being a weak acid due to the sulfonamide group, allowing it to participate in various chemical reactions, including nucleophilic substitutions. The compound is known for its antibacterial properties, making it significant in medicinal chemistry, particularly in the development of sulfa drugs. Its structure allows for interactions with biological targets, specifically bacterial enzymes involved in folate synthesis. Additionally, 2-amino-N-phenylbenzenesulfonamide can undergo various transformations, including sulfonation and acylation, which can be utilized in synthetic organic chemistry. Safety considerations include potential allergic reactions and the need for proper handling due to its biological activity.

2-amino-N-phenylbenzenesulfonamide

27332-20-3: 2-Amino-N-phenyl-benzenesulfonamide, benzenesulfonamide, 2-amino-N-phenyl-, 2-Amino-N-phenylbenzenesulfonamide

2-Amino-N-phenyl-benzensulfonamide is a synthetic, cyclic compound that has been shown to have pharmacological activity. It is an intramolecular hydrogen acceptor and reacts with electron donors such as oxygen or pyridine. The reaction intermediates are the sulfonamide, the amide, and the heterocycle. In x-ray crystallography studies, 2-amino-N-phenylbenzenesulfonamide was found to be a hybridized molecule with a conformation of dihedral angles of about 60 degrees. This molecule has also been described in terms of its anions.

CAS 27332-20-3: 2-amino-N-phenylbenzenesulfonamide

2-Amino-N-phenyl-benzensulfonamide

Ref: 3D-FA157687

2-AMINO-N-PHENYL-BENZENESULFONAMIDE

Ref: IN-DA00BFBX