CAS 274-09-9: 1,3-Benzodioxole

1,3-Benzodioxole is a small molecule that has shown to be cytotoxic in rat liver microsomes and significantly inhibit the polymerase chain reaction. The binding of 1,3-benzodioxole to the active site of bacterial DNA gyrase may lead to irreversible inhibition of the enzyme. 1,3-Benzodioxole has been shown to inhibit the growth of bacteria in an experimental model and is also active against some fungi and parasites. 1,3-Benzodioxole has been shown to have antimicrobial activity against methicillin resistant Staphylococcus aureus (MRSA) isolates by interfering with cell wall biosynthesis.

1,3-Benzodioxole is useful in gemological stimulant detection. It is also used as a precursor for perfumes, photo initiators, agrochemicals and pharmaceuticals. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1,3-Benzodioxole