Pyrazolo[1,5-a]pyrimidine is a heterocyclic compound characterized by a fused ring system that incorporates both pyrazole and pyrimidine moieties. This compound typically exhibits a planar structure, which contributes to its potential for engaging in π-π stacking interactions, making it of interest in various fields, including medicinal chemistry and materials science. Pyrazolo[1,5-a]pyrimidine derivatives often display biological activity, including anti-inflammatory and anticancer properties, due to their ability to interact with specific biological targets. The presence of nitrogen atoms in the ring structure can influence the compound's reactivity and solubility, affecting its pharmacokinetic properties. Additionally, the compound's synthesis often involves cyclization reactions, and it can serve as a building block for more complex molecules. Its unique structural features and biological relevance make pyrazolo[1,5-a]pyrimidine a subject of ongoing research in drug development and organic synthesis.

Pyrazolo[1,5-a]pyrimidine

274-71-5: 1,4,7a-Triazaindene, Pyrazolo[2,3-a]pyrimidine, Pyrazolo[1,5-a]pyrimidine, pyrazolo(1,5-a)pyrimidine

Pyrazolo[2,3-a]pyrimidine

Pyrazolo[1,5-a]pyrimidine is a pyrimidine compound that inhibits the synthesis of gamma-aminobutyric acid (GABA) in the central nervous system. It has been shown to have antimicrobial properties, as well as antihypertensive activity. Pyrazolo[1,5-a]pyrimidine also has an anti-inflammatory effect and can be used to treat infectious diseases, autoimmune diseases, and syncytial virus infections. This drug also has pharmacokinetic properties that are characterized by a short half-life in humans and rapid excretion of unchanged pyrazolo[1,5-a]pyrimidine in urine.
Pyrazolo[1,5-a]pyrimidine binds to the mitochondrial membrane potential by inhibiting fatty acid synthesis and reduces the production of reactive oxygen species (ROS).

CAS 274-71-5: Pyrazolo[1,5-a]pyrimidine

Pyrazolo[2,3-a]pyrimidine

Ref: 10-F223747

Pyrazolo[1,5-a]pyrimidine

Ref: 3D-FP156619

Pyrazolo[1,5-a]pyrimidine

Ref: 54-OR301222

PYRAZOLO[1,5-A]PYRIMIDINE

Ref: IN-DA00BFGF