2-(4-Methoxyphenyl)benzothiophene, identified by its CAS number 27884-09-9, is an organic compound characterized by its unique structure, which features a benzothiophene core substituted with a methoxyphenyl group. This compound typically exhibits properties associated with aromatic compounds, including stability and potential for π-π stacking interactions due to its conjugated system. The presence of the methoxy group enhances its solubility in organic solvents and may influence its electronic properties, making it of interest in various applications, including organic electronics and materials science. Additionally, the thiophene ring contributes to its electronic characteristics, potentially allowing for applications in organic semiconductors or as a building block in the synthesis of more complex molecules. The compound may also exhibit interesting photophysical properties, which could be relevant in the development of dyes or sensors. As with many organic compounds, its reactivity and stability can be influenced by environmental factors such as temperature and light exposure.

2-(4-Methoxyphenyl)benzothiophene

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2-(4-Methoxyphenyl)benzothiophene is a piperidin derivative that has been shown to have estrogenic activity. It was synthesized from 2-chlorobenzothiophene and 4-methoxyaniline. It has been used as a pharmaceutical formulation for the treatment of endometriosis, cancer, and Alzheimer's disease. 2-(4-Methoxyphenyl)benzothiophene has also been shown to be effective in preventing restenosis following angioplasty by inhibiting muscle cell proliferation.
2-(4-Methoxyphenyl)benzothiophene binds to the estrogen receptor alpha (ERα), which prevents it from binding with DNA, thereby preventing transcription and replication. This molecule also inhibits the enzymatic activity of acetylcysteine, which is an antioxidant that protects cells against oxidative damage by free radicals such as hydrogen peroxide or hydroxyl radical

CAS 27884-09-9: 2-(4-Methoxyphenyl)benzothiophene

2-(4-Methoxyphenyl)benzothiophene

Ref: 3D-FM151902