CAS 28537-70-4: 1,4-Bis(maleimido)butane
Formula:C12H12N2O4
InChI:InChI=1S/C12H12N2O4/c15-9-3-4-10(16)13(9)7-1-2-8-14-11(17)5-6-12(14)18/h3-6H,1-2,7-8H2
InChI key:InChIKey=WXXSHAKLDCERGU-UHFFFAOYSA-N
SMILES:C(CCCN1C(=O)C=CC1=O)N2C(=O)C=CC2=O
Synonyms:- 1,1′-(1,4-Butanediyl)bis[1H-pyrrole-2,5-dione]
- 1,4-Bis(maleimide)butane
- 1,4-Bis(maleimido)butane
- 1,4-Di(maleimido)butane
- 1-[4-(2,5-Dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione
- 1H-Pyrrole-2,5-dione, 1,1'- (1,4-butanediyl)bis-
- BMB Crosslinker
- Maleimide, N,N′-tetramethylenedi-
- N,N′-1,4-Butylenebismaleimide
- N,N′-Tetramethylenebis[maleimide]
- N,N′-Tetramethylenedimaleimide
- See more synonyms
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Found 6 products.
1,1?-(Butane-1,4-Diyl)Bis(1H-Pyrrole-2,5-Dione)
CAS:1,1?-(Butane-1,4-Diyl)Bis(1H-Pyrrole-2,5-Dione)Purity:97%Molecular weight:248.24g/mol1,4-Bis(maleimido)butane
CAS:1,4-Bis(maleimido)butane is a chemical compound that binds to the active site of ubiquitin ligases and inhibits their activity. It prevents the addition of ubiquitin to other proteins, which may lead to transcriptional regulation. The compound has been shown to inhibit the proliferation of mammalian cells in culture by interfering with mitotic checkpoint control. This agent is also used as a crosslinker in protein-protein interactions studies, where it is covalently attached to one protein and then reacted with a second protein. 1,4-Bis(maleimido)butane has been shown to be pegylated for use as an anti-inflammatory drug.Formula:C12H12N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:248.23 g/molRef: 3D-FB18729
Discontinued product1,4-Bis(maleimido)butane
CAS:Controlled ProductApplications A short, sulfhydryl reactive homobifunctional crosslinking reagent. References Jahng, W., et al.: Biochem., 41, 7528 (2002),Formula:C12H12N2O4Color and Shape:NeatMolecular weight:248.231,4-Bis(maleimido)butane
CAS:Formula:C12H12N2O4Purity:>98.0%(HPLC)(N)Color and Shape:White to Light yellow to Dark green powder to crystalineMolecular weight:248.241H-Pyrrole-2,5-dione, 1,1'-(1,4-butanediyl)bis-
CAS:Formula:C12H12N2O4Purity:98%Color and Shape:SolidMolecular weight:248.23468000000005
