CAS: 28597-08-2

3,4,5-Trichloro-2,6-dimethylpyridine (3,4,5-TCP) is a chemical compound that is used as a hyperpolarizer in magnetic resonance imaging. Hyperpolarization is a process that increases the polarization of nuclear spins and can be achieved by using 3,4,5-TCP as an agent to transfer the electron spin from one molecule to another. This process is reversible and efficient. This agent binds to ligands such as parahydrogen or iridium complexes and transfers the electron spin efficiently. 3,4,5-TCP has been shown to be effective for catalyzing reactions with nuclei such as Iridium or Rhodium.