3-Hydroxy-2-methylvaleric acid, with the CAS number 28892-73-1, is an organic compound characterized by its carboxylic acid functional group and a hydroxyl group. This compound features a branched-chain structure, which contributes to its unique properties. It is typically a colorless to pale yellow liquid or solid, depending on its purity and form. The presence of both hydroxyl and carboxylic acid groups allows for hydrogen bonding, influencing its solubility in polar solvents such as water and alcohols. This compound is often studied for its potential applications in biochemistry and pharmaceuticals, particularly in metabolic pathways and as a building block for various synthetic processes. Its stability under standard conditions makes it a suitable candidate for further chemical modifications. Additionally, 3-Hydroxy-2-methylvaleric acid may exhibit biological activity, which can be of interest in research related to metabolic disorders or as a precursor in the synthesis of more complex molecules.

3-Hydroxy-2-methylvaleric acid

28892-73-1: 2-Methyl-3-Hydroxypentanoic Acid, 2-Methyl-3-hydroxyvaleric acid, 3-Hydroxy-2-Methylvaleric Acid, Pentanoic Acid, 3-Hydroxy-2-Methyl-, Valeric acid, 3-hydroxy-2-methyl-, β-Hydroxy-α-methylvaleric acid, 3-Hydroxy-2-methylpentanoic acid,  3-Hydroxy-2-methylpentanoic acid

2-Hydroxy-3-methylpentanoic acid (HMVA) is an organic acid generated by L-isoleucine metabolism.  There are 4 stereoisomers of HMVA (2S,3S-HMVA, 2R,3R-HMVA, 2S,3R-HMVA and 2R,3S-HMVA).  HMVA is found in the urine and blood of normal individuals but in very elevated levels in patients with maple syrup urine disease (MSUD). Maple syrup urine disease (MSUD) is an inherited metabolic disease predominantly characterized by neurological dysfunction including psychomotor/delay/mental retardation.

CAS 28892-73-1: 3-Hydroxy-2-methylvaleric acid

3-Hydroxy-2-methylpentanoic acid

Ref: 3D-DBA89273

Pentanoic acid, 3-hydroxy-2-methyl-

Ref: IN-DA002WZ0

3-Hydroxy-2-methylpentanoic acid

Ref: TR-H948758

3-Hydroxy-2-Methylpentadioic Acid

Ref: 4Z-P-219024