CAS 289-80-5: Pyridazine

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Pyridazine

Pyrrolo[1,2-b]pyridazine 1 is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, is obtained by the condensation of pyridazine and pyrrole. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Pyridazine is a heterocyclic compound that contains a pyridine ring. It has the chemical formula CHN, and is a colourless solid. Pyridazine can be synthesized by reacting trifluoroacetic acid with ammonia in the presence of an oxidizing agent. Pyridazine has been shown to have anti-hypertensive activity, and also inhibits molecules that are involved in the synthesis of nitric oxide and thus reduces blood pressure. Pyridazine binds to the active site of gamma-aminobutyric acid receptors, which are inhibitory neurotransmitter receptors, and acts as an inhibitor molecule. The 5-membered heteroaryl ring coordinates with two nitrogen atoms and two oxygen atoms, forming a planar geometry. This molecule has been studied by X-ray diffraction data, electrochemical impedance spectroscopy (EIS) measurements, and thermodynamic data analysis.