CAS 28957-04-2: Oridonin
Formula:C20H28O6
InChI:InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13?,15+,16?,18+,19-,20+/m0/s1
InChI key:InChIKey=SDHTXBWLVGWJFT-VSKLWXMZSA-N
SMILES:O[C@]12[C@]34[C@]([C@]5(C([C@@H]1O)(C(C)(C)CC[C@@H]5O)[H])CO2)(CC[C@]([C@H]3O)(C(=C)C4=O)[H])[H]
Synonyms:- (1alpha,5beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1alpha,5beta,6beta,7beta,9xi,10xi,14S)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1alpha,5beta,6beta,9beta,14S)-1,6,7,14-tetrahydroxy-7,20-epoxykaur-16-en-15-one
- (1α,6β,7α,14R)-7,20-Epoxy-1,6,7,14-tetrahydroxykaur-16-en-15-one
- (6Beta,7Beta)-1,6,7,14-Tetrahydroxy-7,20-Epoxykaur-16-En-15-One
- 6,11b-(Epoxymethano)-6a,9-methano-1H-cyclohepta[a]naphthalene, kaur-16-en-15-one deriv.
- Isodonal
- Isodonol
- Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
- Kaur-16-en-15-one, 7α,20-epoxy-1α,6β,7,14-tetrahydroxy-, (14R)-
- NSC 250682
- See more synonyms
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Found 13 products.
Oridonin
CAS:Oridonin has anticancer activity, might be useful as adjunctive therapy for individuals with lymphoid malignancies, including the lethal disease adult T-cell leukemia.It inhibits tumor growth in glioma by inducing cell cycle arrest and apoptosis, inhibits BxPC-3 cell growth through cell apoptosis.Formula:C20H28O6Purity:95%~99%Molecular weight:364.438Oridonine
CAS:Formula:C20H28O6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:364.44Oridonin
CAS:Oxygen-heterocyclic compoundFormula:C20H28O6Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:364.44Oridonin
CAS:Oridonin, a diterpenoid from Rabdosia rubescens, has anti-tumor, anti-bacterial, and anti-inflammatory properties, inhibiting AKT1/2.Formula:C20H28O6Purity:100% - 99.5%Color and Shape:PowderMolecular weight:364.44Oridonin
CAS:A diterpenoid from Chinese medicinal plant Rabdosia rubescens with anti-inflammatory activity. It is a potent inhibitor of NF-κB and MAPK activation and suppresses the release of proinflammatory cytokines. It is also a covalent inhibitor of NLRP3, a sensor component of NLRP3 inflammasome. In a rodent model for cerebral amyloidosis, oridonin effectively prevented neuroinflammation and Alzheimer’s disease-associated neuropathological changes. It reduced numbers of amyloid-β plaques in mice brain and reversed behaviour and social impairment.Formula:C20H28O6Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:364.44 g/molKaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
CAS:Formula:C20H28O6Purity:98%Color and Shape:SolidMolecular weight:364.4327Oridonin
CAS:Controlled ProductApplications Oridonin is an effective anticancer agent due to its ability to inhibit proliferation and induce apoptosis of human osteosarcoma cells. Blocks Wnt/β-catenin signalling. References Liu, Y. et al.: Int. J. Onc., 45, 795 (2014);Formula:C20H28O6Color and Shape:NeatMolecular weight:364.43Oridonin - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C20H28O6Purity:Min. 95%Color and Shape:PowderMolecular weight:364.44 g/mol
