CAS 29070-92-6: Pachymic acid
Formula:C33H52O5
InChI:InChI=1S/C33H52O5/c1-19(2)20(3)10-11-22(29(36)37)28-25(35)18-33(9)24-12-13-26-30(5,6)27(38-21(4)34)15-16-31(26,7)23(24)14-17-32(28,33)8/h19,22,25-28,35H,3,10-18H2,1-2,4-9H3,(H,36,37)/t22-,25-,26+,27+,28+,31-,32-,33+/m1/s1
InChI key:InChIKey=VDYCLYGKCGVBHN-DRCQUEPLSA-N
SMILES:C[C@]12[C@@](C)([C@@]([C@@H](CCC(C(C)C)=C)C(O)=O)([C@H](O)C1)[H])CCC3=C2CC[C@@]4([C@]3(C)CC[C@H](OC(C)=O)C4(C)C)[H]
Synonyms:- (3b,16a)-3-(Acetyloxy)-16-hydroxy-24-methylenelanost-8-en-21-oic acid
- (3beta,16alpha,20R)-3-(acetyloxy)-16-hydroxy-24-methylidenelanost-8-en-21-oic acid
- 3-(Acetyloxy)-16-Hydroxy-24-Methylidenelanost-8-En-21-Oic Acid
- 3-O-Acetyltumulosic acid
- Eburica-8,24(28)-dien-21-oic acid, 3β,16α-dihydroxy-, 3-acetate
- Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-
- Lanost-8-en-21-oic acid, 3β,16α-dihydroxy-24-methylene-, 3-acetate
- NSC 244427
- Pachymic acid
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Found 9 products.
Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-24-methylene-, (3β,16α)-
CAS:Formula:C33H52O5Purity:99%Color and Shape:SolidMolecular weight:528.7629799999996Pachymic acid
CAS:Carboxylic acid with alcohol functionFormula:C33H52O5Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:528.78Pachymic acid
CAS:Pachymic acid (PA) is a natural triterpenoid known to inhibit the phospholipase A2 (PLA(2)) family of arachidonic acid (AA)-producing enzymes, PA-treatment decreases bad phosphorylation, increases Bcl-2 phosphorylation, and activates caspases-9 and -3, it also decreases the expression and activation of proteins within the AKT signal pathway. suggests that PA initiates apoptosis through mitochondria dysfunction and influences apoptosis by reducing prostaglandin .Formula:C33H52O5Purity:95%~99%Color and Shape:PowderMolecular weight:528.774Pachymic Acid
CAS:Controlled ProductApplications Pachymic Acid is a natural triterpene extract which suppresses invasiveness of pancreatic cancer cells through the downregulation of MMP-7. References Cheng, S. et al.: Int. J. Oncol., 42, 1869 (2013); Wang, P. et al.: J. Sep. Sci., 36, 3511 (2013);Formula:C33H52O5Color and Shape:NeatMolecular weight:528.76Pachymic acid
CAS:Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways.Formula:C33H52O5Purity:100% - 99.91%Color and Shape:White PowderMolecular weight:528.76Pachymic acid
CAS:Controlled ProductPachymic acid is a naturally occurring triterpenoid acid, which is primarily extracted from the sclerotium of Poria cocos, a medicinal fungus widely used in traditional Chinese medicine. It exhibits a range of biological activities attributed to its unique molecular structure. The mode of action of pachymic acid involves the modulation of various signaling pathways, including anti-inflammatory, antioxidant, and apoptotic mechanisms. Additionally, it impacts immune cell regulation and exhibits potential in tumor suppression. Scientists are particularly interested in pachymic acid for its therapeutic applications. Its anti-inflammatory properties make it a candidate for treating inflammatory diseases, while its ability to induce apoptosis and hinder cancer cell proliferation is being explored for anticancer therapies. Moreover, its antioxidative capabilities contribute to neuroprotection, offering possible benefits in neurodegenerative conditions. Current research aims to further elucidate its mechanisms and pave the way for novel pharmacological applications, considering its relatively low toxicity and favorable bioactivity profile. As such, pachymic acid remains an exciting focus of study for its potential contributions to various medical fields.Formula:C33H52O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:528.76 g/mol
