CAS 293753-05-6: SR3335

SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM).

SR3335

N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide is a versatile compound with various applications. It can be used as an anticoagulant, fumigant, and even in the production of steroids. This compound has been found to have beneficial effects on methanol toxicity and oxidative stress by enhancing α-tocopherol levels. Additionally, it has shown potential in reducing particulate emissions from brominated compounds and improving the efficacy of drugs like diclofenac, gabapentin, and creatine. Its unique properties make it a valuable ingredient in several industries.