CAS 294674-09-2: (3β,23S,24E)-3,23-Dihydroxy-7,11,15-trioxolanosta-8,24-dien-26-oic acid

The binding affinities of ganoderic acid DM and ganoderic acid Z (ΔGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug

Ganoderic acid Z is a triterpenoid compound, which is sourced from the medicinal mushroom Ganoderma lucidum, commonly known as Reishi. This compound belongs to a class of bioactive constituents, specifically lanostanoid triterpenes, prevalent in this fungal species. Ganoderic acid Z exerts its effects through various biochemical pathways, primarily involving modulation of oxidative stress, inhibition of inflammatory mediators, and interaction with cellular signaling pathways related to apoptosis and cell cycle regulation. The uses and applications of Ganoderic acid Z extend to potential therapeutic avenues, particularly in the fields of oncology and immunology. This compound has shown promise in preclinical studies for its ability to induce apoptosis in cancer cells, thereby suggesting potential roles in cancer therapy. Additionally, its anti-inflammatory and antioxidant properties lend promise for applications in managing chronic inflammatory conditions. Ongoing research aims to further elucidate its mechanisms and expand its applications, providing valuable insights into its role within a broader therapeutic context.