CAS 2950-43-8: Hydroxylamine-O-sulfonic acid

Amino hydrogen sulphate

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Hydroxylamine-O-sulfonic acid is a molecule that contains nitrogen atoms. It is an organic compound that has been shown to be effective in inhibiting bacterial growth by binding to DNA and blocking the synthesis of proteins. Hydroxylamine-O-sulfonic acid is synthesized from hydrochloric acid and sodium citrate, then reacted with diazonium salt for polymerase chain reaction. This compound has been shown to have a strong inhibitory effect on the production of autoantibodies in mice with autoimmune diseases. The mechanism of action is not yet known but may be due to its ability to bind to toll-like receptor 2 (TLR2) and TLR4 receptors, which are important in signaling pathways.

Hydroxylamine-O-sulfonic acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. It is also used as a polymerization catalyst and an amination reagent. It is involved in the preparation of diazene by reacting with an alkali. It is also used in the inhibition of polychlorinated dibenzo-p-dioxins (PCDD) as well as (polychlorinated biphenyl) PCB formation in co-combustion. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications Hydroxylamine-O-sulfonic Acid is used in the synthesis of quinolones for the benzodiazepine site of GABAA receptors. Also used in the inhibition of PCDD as well as PCB formation in co-combustion. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Nilsson, J. et al.: J. Biomed. Sci. Eng., 5, 1 (2012); Pandelova, M. et al.: J. Hazard. Mat., 149, 615 (2007);